The Impact of Intrauterine TORCH Infections on Fetal and Infant Growth and Development: Clinical Overview and Long-Term Implications
DOI:
https://doi.org/10.31004/joecy.v6i1.8955Keywords:
Congenital Infections, Cytomegalovirus, Fetal Development, Intrauterine Growth Restriction, TORCH InfectionsAbstract
Intrauterine TORCH infections (Toxoplasmosis, Other, Rubella, Cytomegalovirus, Herpes simplex) pose significant risks to fetal and infant growth, causing miscarriage, congenital defects, IUGR, and long-term neurological/sensory impairments. This study aims to review clinical impacts, mechanisms, diagnosis, treatment, and prevention. It employs descriptive qualitative methods via systematic literature review from PubMed/Google Scholar (2019-2024), targeting peer-reviewed articles (n=20-30 purposive sample). Instruments include search protocols and thematic tables; analysis uses content analysis with triangulation. Results reveal high first-trimester transmission risks (e.g., 80% for rubella), manifestations like hepatosplenomegaly/hearing loss, serological/PCR diagnostics, antivirals (e.g., acyclovir), and vaccination strategies. In conclusion, early screening optimizes outcomes via prenatal care.
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Copyright (c) 2026 Allia Nova Putri Rizky, Abdi Lathif Yukahadi, Damas Prakoso, Fatih Darmawansyah, Luthfi Fadhillah P, Martha Laura Sitanggang, M. A. Lathif Kariim, Oktavia Dwi S. R, Qais Maulana G, Raihan Abdullah, Rhevita Apsari, Shafira Nova, Tefi Nadila
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