Faktor-Faktor yang Mempengaruhi Kejadian Epistaksis Berulang: Literature Review
DOI:
https://doi.org/10.31004/joecy.v6i1.7430Keywords:
Antikoagulan, Epistaksis Berulang, Faktor Lokal, Faktor Sistemik, HHTAbstract
Epistaksis berulang meningkatkan beban UGD akibat faktor lokal dan sistemik kompleks; kajian ini bertujuan merangkum pemicu dari studi 2021-2025 melalui literatur naratif kualitatif deskriptif dengan pencarian "Factor AND Recurrent Epistaxis", menyaring 203 artikel menjadi 7 studi (3 case report, 2 retrospektif, 1 kohort, 1 observasional) meliputi 2.192 kasus menggunakan form ekstraksi data terstruktur dan analisis tematik PRISMA; hasil menunjukkan faktor lokal (massa intranasal, trauma swab/kauterisasi silver nitrate HR 2,45, kekeringan musiman) dan sistemik (gagal jantung p=0,001, hipertensi, hemofilia A, HHT, antikoagulan prevalensi 18,1%); kesimpulan merekomendasikan intervensi endoskopik lokal dan pengendalian komorbiditas sistemik untuk kurangi rekurensi plus systematic review/RCT masa depan.
References
Al-Wathinani, A. M., & Goniewicz, K. (2025). Factors associated with recurrent emergency department visits for epistaxis in adults, cross sectional study in two tertiary care hospitals in Riyadh, Saudi Arabia [Letter]. Therapeutics and Clinical Risk Management, 21, 111-112. https://doi.org/10.2147/TCRM.S514794
Alghofili, M., Alwhaibi, B., Alassaf, A., et al. (2024). Factors associated with recurrent emergency department visits for epistaxis in adults, cross sectional study in two tertiary care hospitals in Riyadh, Saudi Arabia. Therapeutics and Clinical Risk Management, 20, 955-962. https://doi.org/10.2147/TCRM.S480084
Creswell, J. W., & Creswell, J. D. (2023). Research design: Qualitative, quantitative, and mixed methods approaches (6th ed.). SAGE Publications. https://doi.org/10.4135/9781071817958
Emzir. (2022). Metodologi penelitian kualitatif: Analisis data (Edisi ke-3). Rajawali Pers.
Farag, N., Alwasiyah, B., & Marglani, O. (2023). Nasal hemophilic pseudotumor in a 2-year-old with recurrent epistaxis: A case report and review of the literature. Journal of Surgical Case Reports, 2023(11), 1-3. https://doi.org/10.1093/jscr/rjad586
Hadar, A., Shaul, C., Ghantous, J., Tarnovsky, Y., Cohen, A., Zini, A., & Peleg, U. (2023). Risk factors for severe clinical course in epistaxis patients. Ear, Nose & Throat Journal, 105(2), 1-5. https://doi.org/10.1177/01455613231189056
Iqbal, A., Bokhari, S. F. H., & Ahmad, S. A. (2023). Pediatric intranasal lobular capillary hemangioma: A case report. International Journal of Surgery Case Reports, 111, Article 108894. https://doi.org/10.1016/j.ijscr.2023.108894
Kennedy, S. J., Haupt, L., & Seedat, R. Y. (2025). The effect of the COVID-19 pandemic on epistaxis and anaemia in patients with hereditary haemorrhagic telangiectasia (HHT) in central South Africa. Orphanet Journal of Rare Diseases, 20(1), 1-13. https://doi.org/10.1186/s13023-025-03777-2
Nakazono, A. (2025). Neoadjuvant chemotherapy-induced downstaging enables R0 craniofacial combined resection in AJCC stage IV olfactory neuroblastoma: A case report of 12-year disease-free survival. Cureus, 17(12), 1-13. https://doi.org/10.7759/cureus.100226
Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., Shamseer, L., Tetzlaff, J. M., Akl, E. A., Brennan, S. E., Chou, R., Glanville, J., Grimshaw, J. M., Hróbjartsson, A., Lalu, M. M., Li, T., Loder, E. W., Mayo-Wilson, E., McDonald, S., ... Moher, D. (2021). The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ, 372, Article n71. https://doi.org/10.1136/bmj.n71
Schafer, A. D., McNutt, M., Fulmer, A., Bourgeois, T., & Elmaraghy, C. A. (2024). Comparing recurrence between cautery techniques in pediatric epistaxis. International Journal of Pediatric Otorhinolaryngology, 176, Article 111779. https://doi.org/10.1016/j.ijporl.2023.111779
Sugiyono. (2022). Metode penelitian kuantitatif, kualitatif, dan R&D. Alfabeta.
Sudaryono. (2021). Metode penelitian pendidikan (Edisi revisi). Graha Ilmu.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Naila Fathiya Isnanto, Zalfa Aditya Putra, Giska Tri Putri, Maya Ganda Ratna

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.







