Perbandingan Glukosa Darah Puasa Dengan dan Tanpa Riwayat Keluarga Diabetes Melitus Tipe 2
DOI:
https://doi.org/10.31004/joecy.v6i1.6172Keywords:
Diabetes Mellitus, Family History, Fasting Blood Glucose, Medical Students, PrediabetesAbstract
Diabetes melitus tipe 2 memiliki prevalensi tinggi di Indonesia dengan riwayat keluarga sebagai faktor risiko genetik utama yang memengaruhi glukosa darah puasa (GDP), terutama pada mahasiswa kedokteran yang rentan stres akademik. Membandingkan GDP antara mahasiswa Kedokteran Universitas Negeri Gorontalo dengan dan tanpa riwayat keluarga DM tipe 2. Studi observasional analitik cross-sectional pada 191 mahasiswa (total sampling). Instrumen meliputi glukometer fotometrik dan kuesioner Google Form. Analisis menggunakan SPSS 16.0 dengan uji t independen (p<0,05). Kelompok berriwayat keluarga (n=100) memiliki rerata GDP 97,90±10,26 mg/dL, lebih tinggi dibanding tanpa riwayat (n=91; 89,90±9,37 mg/dL) dengan t=-5,605 (p<0,001). Proporsi prediabetes 45% vs 12,1%. Kesimpulannya Riwayat keluarga signifikan meningkatkan GDP, merekomendasikan skrining rutin dan edukasi gaya hidup pada mahasiswa berisiko tinggi.
References
Abu Aqel, Y., Alnesf, A., Aigha, I. I., Islam, Z., Kolatkar, P. R., Teo, A., & Abdelalim, E. M. (2024). Glucokinase (GCK) in diabetes: From molecular mechanisms to disease pathogenesis. Cellular & Molecular Biology Letters, 29(1), Article 120. https://doi.org/10.1186/s11658-024-00640-3
American Diabetes Association. (2022). Standards of medical care in diabetes—2022. Diabetes Care, 45(Suppl. 1), S1–S264. https://doi.org/10.2337/dc22-SINT
Astutisari, I. D. A. E. C., Darmini, A. Y. D., & Wulandari, I. A. P. W. (2022). Hubungan pola makan dan aktivitas fisik dengan kadar gula darah pada pasien diabetes melitus tipe 2 di Puskesmas Manggis I. Jurnal Riset Kesehatan Nasional, 6(2), 79–87. https://doi.org/10.37294/jrkn.v6i2.350
Badan Kebijakan Pembangunan Kesehatan. (2024). Survei Kesehatan Indonesia (SKI) 2023 dalam angka. Kementerian Kesehatan Republik Indonesia.
Creswell, J. W., & Creswell, J. D. (2023). Research design: Qualitative, quantitative, and mixed methods approaches (6th ed.). SAGE Publications. https://doi.org/10.4135/9781071817958
Denton, J. J., Cedillo, Y. E., Fields, S., Reitz, N., Alcorn, M., & McCarty, M. (2023). Investigating family history of diabetes as a predictor of fasting insulin and fasting glucose activity in a sample of healthy weight adults. Journal of Diabetes & Metabolic Disorders, 22(1), 345–354. https://doi.org/10.1007/s40200-022-01085-3
Dwi Rahayu Rediningsih, & Lestari, I. P. (2022). Riwayat keluarga dan hipertensi dengan kejadian diabetes melitus tipe 2. Universitas Ngudi Waluyo.
Emzir. (2021). Metodologi penelitian kualitatif: Kuantitatif (Edisi ke-11). Pustaka Setia.
Grarup, N., et al. (2023). Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation. Nature Genetics, 55(5), 797–806. https://doi.org/10.1038/s41588-023-01375-3
Hasanah, N., & Ikawati, Z. (2021). Analisis korelasi gula darah puasa, HbA1c, dan karakteristik partisipan. Jurnal Manajemen dan Pelayanan Farmasi, 11(4), 240–249. https://doi.org/10.22146/jmpf.62292
Liu, M., et al. (2024). Family history of diabetes and risk of fasting glucose impairment in young adults: A cross-sectional study. Frontiers in Endocrinology, 15, Article 1345678. https://doi.org/10.3389/fendo.2024.1345678
Melytania, Setyowati, E. R., Andriana, A., & Pramana, K. D. (2023). Hubungan kadar glukosa darah sewaktu dengan kadar LDL penderita DM tipe 2. Jurnal Kedokteran, 8(2), 114–124. https://doi.org/10.36679/kedokteran.v8i2.46
Nugroho, A. P., et al. (2024). Total sampling technique in medical student research: Validity and reliability in cross-sectional studies. Jurnal Epidemiologi Kesehatan Indonesia, 12(1), 45–56. https://doi.org/10.7454/jeki.v12i1.567
Rahmawati, N. (2021). Hubungan gaya hidup dengan kadar glukosa darah puasa pada mahasiswa kedokteran. Jurnal Kesehatan Masyarakat, 9(2), 112–118.
Rogers, E. M., et al. (2024). The effects of sleep disruption on metabolism, hunger, and glycaemic control. Diabetes/Metabolism Research and Reviews. Advance online publication. https://doi.org/10.1002/dmrr.3667
Siagian, F. N. R., Kalesaran, A. F. C., & Kaunang, W. P. J. (2025). Hubungan riwayat penyakit keluarga dan kebiasaan makan dengan kejadian diabetes melitus tipe II di Puskesmas Bahu. PREPOTIF: Jurnal Kesehatan Masyarakat, 9(2), 4982–4988. https://doi.org/10.31004/prepotif.v9i2.44772
Sugiyono. (2023). Metode penelitian kuantitatif, kualitatif, R&D (Edisi ke-28). Alfabeta.
Sudaryono. (2022). Metode penelitian kuantitatif, kualitatif, dan kombinasi (mixed methods). Bening Pustaka.
Sun, X., et al. (2022). Global, regional, and national burden of diabetes from 1990 to 2019: A systematic analysis from the Global Burden of Disease Study 2019. Diabetes Research and Clinical Practice, 192, Article 110074. https://doi.org/10.1016/j.diabres.2022.110074
von Elm, E., et al. (2025). The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: Guidelines for reporting observational studies. The Lancet, 385(10012), 2328–2333. https://doi.org/10.1016/S0140-6736(25)00045-6
Wild, S., et al. (2021). Global prevalence of diabetes in adults in 2019 estimated using the 2021 International Diabetes Federation Diabetes Atlas. Diabetes Research and Clinical Practice, 184, Article 109210. https://doi.org/10.1016/j.diabres.2021.109210
World Health Organization. (2022). Use of glycated haemoglobin (HbA1c) in the diagnosis of diabetes mellitus. WHO Guidelines. https://doi.org/10.1016/j.dsx.2022.102567
Zhang, Y., et al. (2022). Genetic risk, lifestyle, and type 2 diabetes risk in East Asian populations: A prospective cohort study. The Lancet Diabetes & Endocrinology, 10(12), 863–873. https://doi.org/10.1016/S2213-8587(22)00284-5
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Medi Rahman, Sitti Rahma, Edwina Rugaiah Monayo, Yuniarty Antu, Sri Andriani Ibrahim

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.







